Auteurs
Weisbrot
D, Lin H, Ye L, Blank M, et al. (2003)
The authors used the
fly Drosophila melanogaster (Dm) for this study. They had previously studied
the effects of extremely low frequency fields on Dm, and in this study
they assessed the effect of radiofrequency fields.
The RF fields were
produced by a GSM 1900 MHz cell phone. The flies were exposed for 60 minutes
twice daily for 10 days. Pupae and adult flies were counted daily. Protein
was extracted from larvae for analyses of hsp 70 levels, binding activity
of SRE, and phosphorylation of ELK-1. SRE (serum response element) is
a regulatory sequence in cell metabolism, and ELK-1 is a nuclear transcription
factor. The SAR was approximately 1.4 W/kg.
There were significant
increases in hsp 70 (3.6 fold), SRE (3.7 fold), and ELK-1 phosphorylation
(3.9 fold), compared to sham readings. When an MP12 device was added,
these increases were not so marked. This device has no effect on the ELF
frequencies but did have an effect on the RF frequencies. This suggests
that the less marked increases in the biological changes with the MP 12
device, compared with those seen with the unaltered phone, must have been
due to the RFR being altered. In turn, this suggests that the RFR had
a part to play in the observed changes.
In addition to the
above changes, it was observed that there were increased numbers of Dm
offspring produced by the RFR compared to sham exposure.