The aim of this study was to test the effect of RFR
exposure on the expression of HSPs in the skin of hairless rats. Two
sets of experiments were done. In the first, the right part of the
rat's back was exposed or sham-exposed to RFR at 5 W/kg for 2 hours,
and the animals were then immediately sacrificed and a skin biopsy
taken. In the second experiment, the rats were exposed or sham-exposed
at 2.5 or 5 W/kg for 2 hours a day, 5 days per week, for 12 weeks.
Skin biopsies were taken within 72 hours of the last exposure.
Neither single nor repeated exposures altered HSP expression in rat skin. The HSPs examined were Heat-shock cognate 70, and HSP 25 and 70.