Ferreri F, Curcio G, Pasqualetti P, De Gennaro L, et al. (2006)

The authors used Transcranial Magnetic Stimulation (TMS) to measure brain excitability. TMS is known to provide a reliable measure of cortical excitability both in the motor target area and in its connections, such as the parietal and temporal ones.

Fifteen male volunteers were exposed to RFR from a 900 MHz GSM signal for 45 minutes, or were sham-exposed. The maximum SAR in the active exposure was 0.5W/kg. The subjects were tested in two sessions one week apart, and the design was cross-over and double-blind. The subjects wore a helmet that held GSM phones that were 15mm from the ear. The phone on the right ear had no battery. The left ear phone was either turned on or off at the sessions. Motor Evoked Potentials were recorded using a paired-pulse paradigm, both before and after exposure. Short Intracortical Inhibition (SICI) and Facilitation (ICF) curves were evaluated both on the exposed and non-exposed hemispheres.

The intracortical excitability curve became significantly modified during real exposure, with SICI being reduced and ICF enhanced in the acutely exposed hemisphere as compared to the non-exposed hemisphere or to sham exposure.

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