Anderson LE, Sheen DM, Wilson BW, Grumbein SL, et al. (2004)

This study was designed to measure the effect of the 1.6 GHz Iridium signal on carcinogenesis in Fischer 344 rats.

There were two components of the study. In the first, pregnant rats were assigned to one of three groups. Two groups of 36 animals each were exposed to a far-field radiofrequency radiation (RFR) Iridium signal (Brain SAR in the fetuses 0.16 W/kg), and a third group of 36 rats had sham exposure. A further group of 42 animals were cage controls. The radiation was initiated at 19 days of gestation and was given for 2 hours per day, 7 days per week, until the pups were weaned (~23 days old). There were no statistically significant differences between the exposed and sham groups in the number of live pups per litter, in the survival of the pups, or in the weaning weights.

In the second phase of the study, 90 male and 90 female offspring per group were selected for one of 3 near-field groups. In the first, the rats were exposed to 1.6 W/kg to the head region. In the second the exposure was 0.16 W/kg, and in the third there was sham-exposure. In addition there were 80 males and 80 females that served as cage controls. The RFR was given for 2hours per day, 5 days per week, from 36 days of life until the rats were 2 years old. This phase of the study was blinded. Necropsies and histological examination were done on all animals that died spontaneously, were euthanized due to a moribund condition, or were killed at the termination of the experiment. There were no statistically significant differences between the groups in clinical conditions, cancer incidence, or survival incidence at the end of the exposure.

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